4th International Caparica Conference in SPLICING 2021
26th – 29th July 2021 | Caparica | Portugal
Dear Colleagues and friends
It is estimated that 30% of diseases caused by mutations can be linked to splicing. Mutation of a splice site can result in site loss of function and specificity, causing insertion or deletion of aminoacids or a disruption of the reading frame. The importance of understanding and properly decoding roles governing splicing have become a fact for the research community as demonstarted by the increasing number of manuscripts devoted to this subject. Splicing 2021 intends to join in a friendly academic environment all of us working or interested in moving to this area of research. The conference will take place in summer in one of the best beach areas from Portugal, the sea village of Caparica (South Lisbon area). We aim you to present your latest results in Splicing and to join the best researchers in this area of knowledge. Please do not hesitate in contacting me should you have any suggestion to help us make of this event a remarkable one.
J. L. Capelo
On behalf of the organizing and scientific committee
Lorna Harries, PhD
Affiliation: University of Exeter Medical School, Exeter (UK)
Title: Alternative RNA processing: a new senotherapeutic target?
Benoit Chabot, PhD
Affiliation: Département de microbiologie et d’infectiologie, Faculté de médecine et des sciences de la santé, Université de Sherbrooke (Canada)
Title: A novel class of CLK inhibitors that preferentially target SRSF10 and promote p53-dependent cytotoxicity on human colorectal cancer cells.
Steve Wilton, PhD
Affiliation: Murdoch University (Australia)
Title: Therapeutic alternative splicing: Challenges in developing treatments for inherited diseases.
Ruth Sperling, PhD
Affiliation: Department of Genetics, The Hebrew University of Jerusalem, Jerusalem (Israel)
Title: Quality control of splicing regulation.
Yi Xing, PhD
Affiliation: Center for Computational and Genomic Medicine The Children’s Hospital of Philadelphia (USA)
Title: Alternative splicing in cancer transcriptomes.
Raymond Kaempfer, PhD
Affiliation: Biochemistry and Molecular Biology, Faculty of Medicine, The Hebrew University (Israel)
Frans Cremers, PhD
Affiliation: Department of Human Genetics, Radboud University Medical Center, Nijmegen (The Netherlands)
Title: Stargardt disease-associated deep-intronic variants in ABCA4 result in complex splicing defects.
John Rasko, PhD
Affiliation: Head of Department, Cell & Molecular Therapies, Royal Prince Alfred Hospital, Sydney (Australia)
Title: Changing paradigms of intron retention.
Chonghui Cheng, PhD
Affiliation: Department of Molecular and Human Genetics, Baylor College of Medicine, Houston (USA)
Title: Alternative RNA splicing contributes to cancer cell plasticity.
Matthias Soller, PhD
Affiliation: School of Biosciences, College of Life and Environmental Sciences, University of Birmingham (UK)
Title: Alternative splicing regulation by m6A mRNA methylation in Drosophila sex determination.
Diana Baralle, PhD
Affiliation: University of Southampton, Southampton (UK)
Title: RNA and splicing in Genomic Medicine.
Ihab Younis, PhD
Affiliation: Carnegie Mellon University Qatar (Qatar)
Title: Targeting Deregulated Splicing in Breast Cancer.
Hui Li, PhD
Affiliation: School of Medicine, University of Virginia (USA)
Alexander Hüttenhofer, PhD
Affiliation: Innsbruck Medical University – Biocenter, Innsbruck (Austria)
Title: Intronic tRNAs of mitochondrial origin act as regulators of constitutive and alternative splicing.
David Bates, PhD
Affiliation: Division of Cancer and Stem Cells,School of Medicine,University of Nottingham (UK)
Lucy Donaldson, PhD
Affiliation: University of Nottingham, School of Life Sciences, Nottingham (UK)
Anthony Schweitzer, PhD
Affiliation: Thermo Fisher Scientific, Santa Clara (USA)
Michele Mishto, PhD
Affiliation: Centre for Inflammation Biology and Cancer Immunology (CIBCI) & Peter Gorer Department of Immunobiology, King’s College London, London (UK)
Title: 2004-2021: what we know about post-translational peptide splicing.
Beatrice Eymin, PhD
Affiliation: Institute For Advanced Biosciences, INSERM U1209/CNRS UMR5309/University Grenoble Alpes, Grenoble (France)
Title: Splice variants of the RTK family: their role in tumor progression and response to therapies.
- RNA Splicing
- Protein Splicing
- DNA Splicing
Hotel Aldeia dos Capuchos
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We look forward to seeing you soon.
With kindest regards
The PROTEOMASS BIOSCOPE Team