4th International Caparica Conference in SPLICING 2021
26th – 29th July 2021 | Caparica | Portugal
Benjamin Lee, PhD
Affiliation: University of Exeter (United Kingdom)
Title: Negligible senescence in naked mole rats may be a consequence of well-maintained splicing regulation.
Francois Bordeleau, PhD
Affiliation: CRChu de Québec (HDQ) – Universite Laval (Canada)
Title: Tumor mechanics and alternative splicing: at the crossroad between regulation and adaptation.
Alexandra Filatova, PhD
Affiliation: Research Centre of Medical Genetics, Moscow (Russia)
Title: PAX6 5’-UTR mutations affecting splicing lead to a disruption of protein translation and cause Congenital aniridia.
Corinna Giorgi, PhD
Affiliation: European Brain Research Institute (Italy)
Title: Arc 3’UTR splicing leads to dual and antagonistic effects in fine-tuning Arc expression upon BDNF signaling.
Martin Schroeder, PhD
Affiliation: Durham University (United Kingdom)
Title: An initial phase of JNK activation inhibits cell death early in the endoplasmic reticulum stress response.
Nicola Jeffery, PhD
Affiliation: University of Exeter (United Kingdom)
Title: Cellular stressors may alter islet hormone cell proportions by moderation of alternative splicing patterns.
Penelope Morel, PhD
Affiliation: University of Pittsburgh (United States)
Title: The role of RNA processing factors in regulatory T cell differentiation: does splicing matter?
Tal Shay, PhD
Affiliation: Ben-Gurion University of the Negev (Israel)
Title: The splicing program of the immune system.
Olivier Pardo, PhD
Affiliation: Imperial College (United Kingdom)
Title: hnRNPA1 promotes cancer progression in response to FGF2 signalling.
Kristel Sleegers, PhD
Affiliation: VIB-UAntwerp Center for Molecular Neurology (Belgium)
Title: Splicing of ABCA7 and risk of Alzheimer’s disease.
Julia E. Weigand, PhD
Affiliation: Technische Universität Darmstadt (Germany)
Title: Muscleblind-like 2 controls the hypoxia response of cancer cells.
Veronica Arora, PhD
Affiliation: Institute of Genetics and Genomics, Sir Ganga Ram Hospital, New Delhi (India)
Title: The first case of antenatal presentation in COG related Congenital Disorders of Glycosylation: a novel splice site mutation.
Eduardo Eyras, PhD
Affiliation: Australian National University (Australia)
Title: Unshackling transcriptomes from genome references.
Eiichi Saitoh, PhD
Affiliation: Graduate School of Technology, Niigata Institute of Technology (Japan)
Title: Expression of proline-rich proteins, P-B1, P-B, and BPLP, the parent proteins of opiorphin family, in human saliva.
Enrico Schleiff, PhD
Affiliation: Goethe University & FIAS (Germany)
Title: Splicing as central regulatory element of the plant heat stress response.
Mubeen Khan, PhD
Affiliation: Radboud university medical center, Nijmegen (Netherlands)
Title: Non-coding (splice) variants resolve the missing heritability in ABCA4-associated Stargardt disease.
Maayan Salton, PhD
Affiliation: Hebrew University (Israel)
Title: KDM3A regulates alternative splicing of cell-cycle genes following DNA damage.
Steven Fisher, PhD
Affiliation: University of Maryland School of Medicine (United States)
Title: Alternative splicing determines vascular smooth muscle function: Focus on myosin phosphatase splice variants and their targeting for therapeutic gain.
Luciana Haddad, PhD
Affiliation: Universidade de São Paulo (Brazil)
Title: Human DNA variants affecting pre-mRNA splicing: an NGS perspective.
Tracy Kress, PhD
Affiliation: The College of New Jersey (United States)
Title: Acetylation of Histones H4 and H2A.Z by the NuA4 acetyltransferase is Required for Appropriate RNA Splicing in Saccharomyces cerevisiae.
Giulia Fontemaggi, PhD
Affiliation: Oncogenomic and Epigenetic Unit, IRCCS Regina Elena National Cancer Institute (Italy)
Title: The ID4/mutant p53 protein complex enhances proliferation of breast cancer cells through the modulation of alternative splicing.
Beverly Chilton, PhD
Affiliation: Texas Tech University HSC (United States)
Title: Alternative splicing of helicase-like transcription factor (Hltf) promotes immune tolerance in murine placenta.
Wei Guo, PhD
Affiliation: University of Wisconsin-Madison (USA)
Title: Phosphorylation of RBM20 on RS Domain Plays A Key Role in The Development of Heart Failure.
Dmitri Pervouchine, PhD
Affiliation: Skolkovo Institute of Science and Technology (Russia)
Title: Global cross-regulatory network couples the expression and alternative splicing of RNA-binding proteins by nonsense-mediated mRNA decay.
Sandra Cooper, PhD
Affiliation: The University of Sydney; The Children’s Hospital at Westmead; The Children’s Medical Research Institute (Australia)
Title: Pathogenic Abnormal Splicing Due to Intronic Deletions that Induce Biophysical Space Constraint for Spliceosome Assembly.
Yuichi Shiraishi, PhD
Affiliation: National Cancer Center (Japan)
Title: An atlas of intron retention associated variants collected by cloud-based transcriptome analysis platform.
Logan Walker, PhD
Affiliation: University of Otago (New Zealand)
Title: Assessment of cancer susceptibility gene mRNA splicing with implications for variant classification.
Takuro Miyazaki, PhD
Affiliation: Showa University (Japan)
Title: Defective exon junction complex disturbs cholesterol handling in macrophages thereby exacerbating atherosclerosis.
Mihwa Lee, PhD
Affiliation: La Trobe University (Australia)
Title: Cytoplasmic accumulation of the RNA-binding protein SFPQ by zinc-induced polymerization.
Shalini Sharma, PhD
Affiliation: University of Arizona, College of Medicine-Phoenix (United States)
Title: Impact of Splicing Factor Mutations on Human Hematopoietic Stem and Progenitor Cells.
Dorota Kaminska, PhD
Affiliation: Institute of Public Health and Clinical Nutrition, University of Eastern Finland (Finland)
Title: Obesity and weight loss-related alternative splicing in adipose tissue.
Nicolas Wein, PhD
Affiliation: The Ohio State University (USA)
Title: AAV.U7 induced exon skipping for two mutational hotspots of the DMD gene (~6%) results in efficient exon skipping, protein restoration and force improvement.
Jesús Valdés Flores, PhD
Affiliation: Departamento de Bioquímica, Centro de Investigación y de Estudios Avanzados (Mexico)
Title: Expression of splicing derived circular RNAs in virulent strains of the protozoan parasite Entamoeba histolytica.
Petra Kleiblova, PhD
Affiliation: Charles University, First Faculty of Medicine, Institute of Biology and Medical Genetics (Czech Republic)
Title: NGS-based analyses of RNA as a tool in oncogenetics.
Stephen M. Mount, PhD
Affiliation: Univ. of Maryland (United States)
Title: Yanagi provides fast and interpretable segment-based alternative splicing and gene expression analysis.
Mikhail Skoblov, PhD
Affiliation: Laboratory of Functional Genomics, Research Centre for Medical Genetics (Russia)
Title: Approaches to the analysis of variants affecting splicing in hereditary diseases.
Liliana Florea, PhD
Affiliation: Johns Hopkins University (United States)
Title: High performance tools for analysis of large collections of RNA-seq data.
Gustavo Bressan, PhD
Affiliation: Department of Biochemistry and Molecular Biology – Federal University of Viçosa (Brazil)
Title: Pharmacological intervention of splicing in cancer: targeting the serine/arginine protein kinases (SRPK) to control metastatic melanoma.
Patrick Burgon, PhD
Affiliation: Qatar University (Qatar)
Title: Avaliable soon.
Isaac Edery, PhD
Affiliation: Rutgers University (United States)
Title: Splicing of a thermosensitive intron influences midday siesta via trans-regulation of a nearby oppositely oriented gene.
Affiliation: Texas Southern University, USA
Title: Avaliable soon.